Patient assistance program for oxycontin

Life-threatening respiratory depression is more likely to occur in elderly, cachectic, or debilitated patients because they may have altered pharmacokinetics or altered clearance compared to younger, healthier patients. Monitor such patients closely, particularly when initiating and titrating OxyContin and when OxyContin is given concomitantly with other drugs that depress respiration. Alternatively, consider the use of non-opioid analgesics in these patients.

Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. If adrenal insufficiency is suspected, confirm the diagnosis with diagnostic testing as soon as possible. If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids.

Wean the patient off of the opioid to allow adrenal function to recover and continue corticosteroid treatment until adrenal function recovers. OxyContin may cause severe hypotension including orthostatic hypotension and syncope in ambulatory patients. There is an increased risk in patients whose ability to maintain blood pressure has already been compromised by a reduced blood volume or concurrent administration of certain CNS depressant drugs e.

Monitor these patients for signs of hypotension after initiating or titrating the dosage of OxyContin. In patients with circulatory shock, OxyContin may cause vasodilation that can further reduce cardiac output and blood pressure. Avoid the use of OxyContin in patients with circulatory shock. In patients who may be susceptible to the intracranial effects of CO 2 retention e.

Monitor those patients for signs of sedation and respiratory depression, particularly when initiating therapy with OxyContin. Opioids may obscure the clinical course in a patient with a head injury. Avoid the use of OxyContin in patients with impaired consciousness or coma.

There have been post-marketing reports of difficulty swallowing OxyContin tablets. These reports include choking, gagging, regurgitation, and tablets stuck in the throat. Instruct patients not to pre-soak, lick or otherwise wet OxyContin tablets prior to placing in the mouth, and to take one tablet at a time with enough water to ensure complete swallowing immediately after placing in the mouth. There have been rare post-marketing reports of cases of intestinal obstruction, and exacerbation of diverticulitis, some of which have required medical intervention to remove the tablet.

Patients with underlying GI disorders such as esophageal cancer or colon cancer with a small gastrointestinal lumen are at greater risk of developing these complications.

Consider use of an alternative analgesic in patients who have difficulty swallowing and patients at risk for underlying GI disorders resulting in a small gastrointestinal lumen. OxyContin is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus.

The oxycodone in OxyContin may cause spasm of the sphincter of Oddi. Opioids may cause increases in the serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis. The oxycodone in OxyContin may increase the frequency of seizures in patients with seizure disorders, and may increase the risk of seizures occurring in other clinical settings associated with seizures.

Monitor patients with a history of seizure disorders for worsened seizure control during OxyContin therapy. Do not abruptly discontinue OxyContin in a patient physically dependent on opioids.

When discontinuing OxyContin in a physically dependent patient, gradually taper the dosage. Rapid tapering of oxycodone in a patient physically dependent on opioids may lead to a withdrawal syndrome and return of pain. When discontinuing OxyContin, gradually taper the dosage. Do not abruptly discontinue OxyContin. OxyContin may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of OxyContin and know how they will react to the medication.

Not every urine drug test for "opioids" or "opiates" detects oxycodone reliably, especially those designed for in-office use. Further, many laboratories will report urine drug concentrations below a specified "cut-off" value as "negative. OxyContin may increase the risk of serious adverse reactions such as those observed with other opioid analgesics, including respiratory depression, apnea, respiratory arrest, circulatory depression, hypotension, or shock. Intended for healthcare professionals of the United States of America only.

Purdue accepts no responsibility for any of the content of the linked site. Do you wish to leave OxyContin. Terms and Conditions Patient must meet eligibility requirements.

Limitations of Use. Life-Threatening Respiratory Depression Serious, life-threatening, or fatal respiratory depression may occur with use of OxyContin.

Accidental Ingestion Accidental ingestion of even one dose of OxyContin, especially by children, can result in a fatal overdose of oxycodone [see Warnings and Precautions 5.

Neonatal Opioid Withdrawal Syndrome Prolonged use of OxyContin during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts.

Cytochrome P 3A4 Interaction The concomitant use of OxyContin with all cytochrome P 3A4 inhibitors may result in an increase in oxycodone plasma concentrations, which could increase or prolong adverse drug effects and may cause potentially fatal respiratory depression. Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants Concomitant use of opioids with benzodiazepines or other central nervous system CNS depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death [see Warnings and Precautions 5.

Reserve concomitant prescribing of OxyContin and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation. Contraindications OxyContin is contraindicated in patients with: Significant respiratory depression Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment Known or suspected gastrointestinal obstruction, including paralytic ileus Hypersensitivity e.

Patient agrees to report their use of this offer to any third party that reimburses or pays for any part of the prescription price. Patient additionally agrees that they will not submit any portion of the product dispensed pursuant to this card to a federal or state healthcare program for purposes of counting it toward their out-of-pocket expenses.

This offer has no cash value and is not valid with any other program, discount, or incentive involving the covered medication. Use of this offer must be consistent with all relevant health insurance requirements and payer agreements. Participating patients, pharmacies, physician offices, and hospitals are obligated to inform third-party payers about the use of the offer as provided for under the applicable insurance or as otherwise required by contract or law.

This offer may not be sold, purchased, traded, or offered for sale, purchase, or trade. This offer is limited to one per person during the offering period and is not transferable. This offer is not contingent upon any past, present, or future purchases of the covered medication or any other product, and this offer may be rescinded, revoked, or amended without notice.

Consult your doctor if this medication isn't relieving the pain sufficiently. May cause constipation, lightheadedness, stomach upset, dizziness, drowsiness, nausea, and flushing. If these effects persist or worsen, contact your doctor.

Notify your doctor if you develop: irregular heartbeat, anxiety, tremors, seizures. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Before using this drug, tell your doctor your medical history, especially: severe diarrhea, stomach or intestinal disorders, breathing problems, kidney or liver disease, history of alcohol use, drug dependence, any allergies. Alcoholic beverages may increase the effects of this drug causing dizziness or lightheadedness.

Limit alcohol intake. Use caution engaging in activities requiring alertness such as driving. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of this drug. The medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Oxycodone is excreted into breast milk. Though, to date, problems have not been reported in nursing infants, consult your doctor before breast-feeding.

Before using this drug, tell your doctor of all the medications you may use, both prescription and nonprescription, especially: cimetidine, alcohol use. Tell your doctor if you take drugs that cause drowsiness such as: medicine for sleep, sedatives, tranquilizers, anti-anxiety drugs e.